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The Chandran Lab

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The Chandran Lab
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May 14, 2025

Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus→

May 14, 2025/ Kartik Chandran
Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus

Wang et al, mBio 2025

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May 14, 2025/ Kartik Chandran/ Comment /Source
researchpage, 2025
April 27, 2025

SuFEx-enabled high-throughput medicinal chemistry for developing potent tamoxifen analogs as Ebola virus entry inhibitors (Copy)→

April 27, 2025/ Kartik Chandran
SuFEx-enabled high-throughput medicinal chemistry for developing potent tamoxifen analogs as Ebola virus entry inhibitors (Copy)

Dada et al, Front Immunol 2025

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April 27, 2025/ Kartik Chandran/ Comment /Source
researchpage, 2025
February 19, 2025

Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread→

February 19, 2025/ Kartik Chandran
Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread

Pahmeier et al, Sci Transl Med 2025

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February 19, 2025/ Kartik Chandran/ Comment /Source
researchpage, 2025
February 12, 2025

Structural insights into tecovirimat antiviral activity and poxvirus resistance→

February 12, 2025/ Kartik Chandran
Structural insights into tecovirimat antiviral activity and poxvirus resistance

Vernuccio et al, Nat Microbiol 2025

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February 12, 2025/ Kartik Chandran/ Comment /Source
researchpage, 2025
January 23, 2025

Engineering and structures of Crimean-Congo hemorrhagic fever virus glycoprotein complexes→

January 23, 2025/ Kartik Chandran
Engineering and structures of Crimean-Congo hemorrhagic fever virus glycoprotein complexes

McFadden et al, Cell 2024

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January 23, 2025/ Kartik Chandran/ Comment /Source
researchpage, 2025
January 15, 2025

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning→

January 15, 2025/ Kartik Chandran
Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Lasso et al, Cell Host & Microbe 2025

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January 15, 2025/ Kartik Chandran/ Comment /Source
researchpage, 2025

© 2015, Kartik Chandran Laboratory