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Human, nonhuman primate, and bat Cells Are broadly susceptible to tibrovirus particle cell entry→
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Cai C et al, Front Microbiol 2019
Read MoreStructural basis of broad ebolavirus neutralization by a human survivor antibody→
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West BR & Wec AZ et al, Nat Struct Mol Biol 2019
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IFITM3 directly engages and shuttles incoming virus particles to lysosomes→
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Spence JS et al, Nature Chem Bio 2019
Read MoreDevelopment of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection→
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Wec AZ et al, Cell Host Microbe 2019
Read MoreA Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates→
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Bornholdt ZA et al, Cell Host Microbe 2019
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Ebola virus, but not Marburg virus, replicates efficiently and without required adaptation in snake cells.→
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Fedewa G et al, Virus Evol 2018
Read MoreProtocadherin-1 is essential for cell entry by New World hantaviruses→
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Jangra RK et al, Nature 2018
Read MoreThe discovery of Bombali virus adds further support for bats as hosts of ebolaviruses→
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Goldstein T et al, Nat Microbiol 2018
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A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus→
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Gunn BM et al, Cell Host Microbe 2018
Read MoreA naturally occurring antiviral ribonucleotide encoded by the human genome→
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Gizzi AS et al, Nature 2018
Read MoreDesign and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins→
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Nyakatura EK et al, J Biol Chem 2018
Read MoreStructural basis for antibody-mediated neutralization of Lassa virus→
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Hastie KM et al, Science 2017
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A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses→
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Wec AZ et al, Science 2016
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